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Programmed intermittent bolus infusion vs continuous infusion of 0.2% levobupivacaine after ultrasound-guided thoracic paravertebral block for video-assisted thoracoscopic surgery: A randomised controlled trial

European Journal of Anaesthesiology Mar 07, 2019

Taketa Y, et al. - In this randomised controlled study, researchers compared the analgesia from intermittent bolus infusion with that of a continuous infusion after thoracic paravertebral block. The study included 70 patients planned for video-assisted thoracoscopic surgery. After an initial 15 ml bolus injection of 0.2% levobupivacaine, patients were randomly assigned to receive 0.2% levobupivacaine through continuous infusion or programmed intermittent bolus infusion. No significant difference was found between the continuous and bolus groups in the postoperative consumption of fentanyl and postoperative pain scores within 24 h. According to findings, postoperative pain and opioid use are similar to either programmed intermittent bolus infusion or thoracic paravertebral block continuous infusion. The study findings suggested that programmed intermittent bolus infusion provides a wider sensory blockage and might benefit patients requiring wider anaesthesia.
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