El Amrousy D, et al. - During this study, authors attempted to investigate the prognostic value of apelin, an endogenous inotrope in children with heart failure (HF) due to congenital heart disease (CHD). Eligible candidates underwent chest X-ray, electrocardiogram (ECG), echocardiography, and laboratory investigations such as complete blood count, c-reactive protein, and serum apelin levels. Serum apelin level demonstrated a prominent positive association with left ventricular systolic function. It also illustrated a significant negative link with heart rate, respiratory rate, Ross classification, c-reactive protein, cardiothoracic ratio, and both left and right ventricular dimensions. As per the findings, serum apelin level served as a good predictive value for adverse outcome in children with HF due to CHD.