Peter RS, Jaensch A, Mons U, et al. - This study was carried out to assess the prognostic value of these trajectories of symptoms of depression with the risk of incident diabetes mellitus (DM) in patients with stable coronary heart disease. Researchers recruited a total of 1,048 patients (mean age 59.4 years, 15% female) with information on prevalent DM at baseline and follow-up data. They used Cox proportional hazards models to model the risk for incident DM during follow-up by depression trajectory class adjusted for age, gender, education, smoking status, body mass index, and physical activity. Following a trajectory of high stable symptoms of depression was correlated with an elevated risk of incident DM in patients with coronary heart disease (CHD). Moreover, incident DM in these patients was correlated with a substantially elevated risk of subsequent cardiovascular events. In patients with CHD, distinguishing depressive symptoms and pertinent treatment offers might be an important and promising approach to enhance outcomes, which should be followed up in future study and practice.