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Prognostic impact of preoperative comorbidities in geriatric patients with early-stage lung cancer: Significance of sublobar resection as a compromise procedure

Lung Cancer Oct 04, 2018

Yutaka Y, et al. - In this retrospective study, researchers assessed the perioperative safety and long-term survival of palliative sublobar resection (SR) in geriatric patients with early-stage lung cancer. For this investigation, 232 patients (141 male, 91 female) aged ≥75 years who had surgical resection of clinical stage I lung cancer from 2006 to 2014 were reviewed. Findings revealed that age, tumor size on computed tomography, central tumor location, and high Adult Comorbidity Evaluation 27 (ACE-27) scores were significantly related to the selection of SR. In selected geriatric patients with clinical stage I lung cancer, the severity of preoperative comorbidities is a significant prognostic factor, and SR as a compromise surgical procedure might provide promising short- and long-term outcomes. It was noted that the ACE-27 score was a more significant prognostic factor than the type of surgical procedure, as well as consolidation/tumor ratio and nodal metastatic status.

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