Ford JR, Rubin ML, Frank SJ, et al. - Using Cox proportional hazards regression models, researchers sought to identify prognostic factors for local recurrence, distant metastasis, and disease-specific survival (DSS) for lacrimal gland carcinoma. From January 1998 through December 2018, all consecutive patients with lacrimal gland carcinoma treated have been involved. Overall, 55 patients were involved, and 5 patients were eliminated from the survival analysis. No significant difference was found in risks of local recurrence, distant metastasis or DSS between ACC patients who had orbital exenteration and those who had eye-sparing surgery. For carcinoma of the lacrimal gland, orbital exenteration with adjuvant therapy and eye-sparing surgery with adjuvant therapy are associated with similar outcomes of recurrence. Findings suggested an association of eye-sparing surgery with better DSS. Perineural invasion is a contributing factor for local recurrence. Basaloid/solid subtype ACC correlates with worse DSS.