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Primary transoral robotic surgery +/- adjuvant therapy for oropharyngeal squamous cell carcinoma: A large observational single-centre series from the United Kingdom

Clinical Otolaryngology Jun 05, 2021

O’Hara J, Warner L, Fox H, et al. - Through this observational case series, researchers attempted to determine the oncological results after primary Transoral Robotic Surgery (TORS) for oropharyngeal squamous cell carcinoma (OPSCC). Participants were all consecutive patients receiving primary TORS with curative intent, with or without adjuvant treatment. There were 120 patients receiving TORS with minimum 12-month follow-up data. TORS alone was the treatment modality in 39 (33%) cases, 50 (42%) underwent adjuvant radiotherapy and 31 (26%) had adjuvant radiotherapy with chemotherapy. Fifteen recurrences occurred. For all patients, survival at 3 years was estimated to be: overall 85%, disease-specific 90%, progression-free 86% and locoregional control 90%. Whilst TORS has emerged as a common practice in OPSCC management in the UK, these represent the first documented oncological results. Findings demonstrate the aptness of TORS with or without adjuvant therapy for selected patients.

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