Prevention of contrast-induced nephropathy by adequate hydration combined with isosorbide dinitrate for patients with renal insufficiency and congestive heart failure
Clinical Cardiology Aug 03, 2018
Qian G, et al. - In order to reduce the risk of contrast-induced nephropathy (CIN) and at the same time avoid acute heart failure, authors explored adequate hydration with nitrates for patients with chronic kidney disease (CKD) and congestive heart failure (CHF). Consecutive patients with CKD and CHF undergoing coronary procedures were randomized to either adequate hydration with nitrates or routine hydration. In patients with CKD and CHF, the risk of CIN could be safely and effectively reduced by adequate hydration with nitrates. During the 90-day follow-up, lower cumulative major adverse events (death, myocardial infarction, stroke, hospitalization for acute heart failure) were seen in the adequate hydration with nitrates group.
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