Yuliati A, Federman M, Rao LM, et al. - Researchers performed this retrospective, single-center analysis to determine the risk factors for death in pediatric extracorporeal membrane oxygenation patients. This study involved all neonatal as well as pediatric patients needing extracorporeal membrane oxygenation at experts’ institution between January 2014 and December 2018, who received a standardized continuous electroencephalogram neuromonitoring protocol during most of the span of extracorporeal membrane oxygenation support. Patients with extracorporeal membrane oxygenation started at another institution were eliminated. Findings demonstrated that children needing extracorporeal membrane oxygenation support commonly developed seizures, with a high rate of electrographic seizures and status epilepticus, as in previous investigations. The factor that conferred risk for both mortality and seizures was the presence of cerebral edema. Extracorporeal cardiopulmonary resuscitation, high lactate concentrations, and prolonged deep hypothermic circulatory arrest were identified as other risk factors for mortality.