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Prevalence of positive coeliac disease serology and HLA risk genotypes in a multiethnic population of adults in Canada: A cross-sectional study

BMJ Open Oct 13, 2017

Jamnik J, et al. - Here, researchers ascertain the prevalence of positive coeliac disease (CD) serology in a population of Canadian adults living in Toronto and aim to figure out if the prevalence of CD seropositivity and predisposing human leucocyte antigen (HLA)-DQ2/DQ8 risk genotypes differ between major ethnocultural groups. The outcome revealed that the prevalence of positive CD serology among Canadian adults living in Toronto is likely ∼1%, with 87% of cases being undiagnosed. These outcomes recommend the requirement for better screening in high genetic risk groups.
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