Jfri A, Nassim D, O’Brien E, et al. - The overall prevalence of hidradenitis suppurativa/acne inversa (HS) was found to be 0.40% in this systematic review and meta-regression analysis. Such findings may aid in policy formulation, funding channelling, and guiding principles for better disease diagnosis and management using universally valid tools.

• The Meta-analysis of Observational Studies in Epidemiology reporting guideline was used for this review and meta-regression analysis.

• Only prevalence estimates from Western European and Scandinavian countries, the United States, and Australia were reported in the 16 quantitatively assessed studies included.

• After adjusting for publication bias in the prevalence estimates, a random effects meta-analysis revealed a 0.40% prevalence for HS.

• Clinical-sample studies revealed a higher pooled prevalence of HS (1.7%) than population-based studies (0.3%).