Prevalence of heart failure and other risk factors among first-degree relatives of women with peripartum cardiomyopathy
Heart Mar 29, 2019
Christiansen MN, et al. - Researchers examined 61 women with peripartum cardiomyopathy (PPCM) in nationwide Danish registers from 2005 to 2014 to determine heart failure and hypertension prevalence in first-degree relatives of these women. A total of 13 women lacked data on relatives and therefore, were excluded from the study. Using a case–control design, they matched (on age, year of childbirth, parity and number of siblings) 48 remaining women to 477 birth-giving Danish women without heart failure. Using the National Danish Registers, they gathered data on first-degree relatives (parents and siblings). In a cohort of validated PPCM cases vs in controls, a significantly higher prevalence of heart failure was reported among first-degree relatives. This was suggestive of a shared etiology between PPCM and other forms of heart failure.
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