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Prevalence and risk factors for hypercalcemia among non-dialysis patients with chronic kidney disease-mineral and bone disorder

International Urology and Nephrology Jun 13, 2018

Seng JJB, et al. - Researchers determined the prevalence and risk factors for hypercalcemia among non-dialysis chronic kidney disease (CKD) patients with mineral and bone disorder (MBD) in this retrospective cohort study carried out in Singapore General Hospital, involving all CKD stage 4 and 5 pre-dialysis patients who were on treatment for MBD in June 2016. Excluded subjects included patients on dialysis, post-renal transplant, post-parathyroidectomy or had no calcium levels taken during the study period. Findings demonstrated that a significant proportion of pre-dialysis patients with MBD were influenced by hypercalcemia. The factors that showed association with increased hypercalcemia risk even after adjusting for covariates included lower baseline iPTH level, history of hypercalcemia in past 1 year and immobility.
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