Hu Z, Zhang L, Lin Z, et al. - The present study was conducted to evaluate the prevalence of bone loss among patients with rheumatoid arthritis (RA) and healthy controls (HC) and the risk factors for osteopenia and osteoporosis of RA patients were further investigated. Researchers designed a cross-sectional survey in four hospitals in different districts in South China to reveal the prevalence of bone loss in patients. They obtained case records, laboratory tests, and bone mineral density (BMD) results of patients. They enrolled 405 patients with RA and 198 HC. The results showed that RA patients were more prone and earlier to have bone loss than HC. There is a need for more attention for measuring BMD in RA patients aging with lower BMI or hyperuricemia. The findings revealed that serum vitamin D and all three measurement sites are recommended to check routinely. Furthermore, TNFi usage in the last year might benefit bone mass.