Gingrich A, et al. - In this cross-sectional study, researchers investigated the prevalence of sarcopenia, frailty, cachexia and malnutrition and their overlap in older medical inpatients. From the Internal Medical Department of a German university hospital, they included 100 patients (48 female) aged 76.5 ± 4.7 years with a BMI of 27.6 ± 5.5 kg/m². Gastroenterological (33%) and oncological diseases (31%) were mainly diagnosed in these patients. Sarcopenia, frailty, cachexia, and malnutrition were present in 42%, 33%, 32% and 15% of the patients, respectively. At least one syndrome was evident in 63%: 32% had one, 11% had two, 12% had three and 8% had all four. These findings suggest the presence of at least one of the tissue loss syndromes sarcopenia, frailty, cachexia and malnutrition in approximately two-thirds of older medical inpatients and partial overlap and interrelation of the syndromes.