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Prevalence and 30-day all-cause mortality of carbapenem and colistin resistant bacteraemias caused by Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumoniae: A description of a decade long trend

International Journal of Infectious Diseases May 19, 2019

Balkhair A, et al. - Researchers examined adult patients with positive blood cultures for Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii to determine the burden of carbapenem and colistin resistance in these organisms in Oman. A worryingly growing prevalence of carbapenem resistant K. pneumoniae, A. baumannii, and P. aeruginosa bacteremias has been reported in Oman, with a large share of K. pneumoniae and P. aeruginosa showing additional resistance to colistin. In 2007, the rates of carbapenem resistance in P. aeruginosa, A. baumannii, and K. pneumoniae bacteremia were 20%, 67% and 0%, respectively, which grew to 25%, 86% and 35% in 2016, respectively. A higher 30-day all-cause mortality was evident in patients with carbapenem resistant bacteremias.

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