Nedergaard HK, et al. - A substudy of the multicenter NONSEDA-trial was conducted to evaluate whether non-sedation influenced the occurrence of pressure ulcers. The outcome of this study revealed that the non-sedation did not significantly decrease the number of pressure ulcers. Non-sedation significantly influenced the location of ulcers: non-sedated patients mainly had ulcers associated with equipment, whereas sedated patients mainly had ulcers on the sacrum and heels.