Nurkic S, et al. - In squamous cell carcinoma of the supraglottic larynx treated with primary radiotherapy (RT), experts assessed the ability of pretreatment computed tomography to predict local control (LC). Pretreatment diagnostic computed tomographic imaging of the larynx and neck was performed in 167 patients, which described primary tumor volume (PrTV). Patients most likely to experience LC with primary RT alone or combined chemoradiation were identified by the pretreatment primary tumor volume (PrTV). Findings suggested optimal LC for supraglottic larynx squamous cell carcinoma if the PrTV is <5.0 cm³. PrTV was seen to be a significant predictor of LC and LC with preserved larynx function; as seen on multivariate analysis.