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Preoperative serum apolipoprotein A-I levels predict long-term survival in non-muscle-invasive bladder cancer patients

Cancer Management and Research May 21, 2018

Shang Z, et al. - Researchers ascertained the relationship between apolipoprotein A-I (Apo A-I) and overall survival (OS) as well as cancer-specific survival (CSS) in non-muscle-invasive bladder cancer (NMIBC) patients undergoing transurethral resection of a bladder tumour (TURBT). As per data, for therapeutic decision making in NMIBC patients, Apo A-I level could potentially serve as a useful prognostic indicator. Findings suggested an association of higher albumin, Apo A-I, and haemoglobin levels with greater OS and CSS, whereas, an association of elevated neutrophil-lymphocyte ratio with worse OS and CSS in the overall and high-risk population rather than low- and the intermediate-risk population was noted. Also, in the overall population and high-risk patients, Apo A-I was shown to be an independent predictor.
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