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Pregnancy outcomes in patients with heart disease in China

The American Journal of Cardiology Apr 15, 2020

Hu J, et al. - Researchers investigated pregnancy outcomes of patients with heart disease in a single center. In addition, they examined the risk factors of adverse outcomes. They retrospectively included 1,033 pregnant women with heart disease from 2010 to 2017. Among 1,086 reported pregnancies, 295 (27.1%) were with congenital heart disease, 244 (22.5%) with rheumatic heart disease, 387 (35.6%) with arrhythmia, and 55 (5.1%) with cardiomyopathy. Eight (0.7%) maternal deaths were reported. Following were the risk factors of mortality: New York Heart Association (NYHA) classification IV, cardiac surgery during pregnancy, and general anesthesia. Worse maternal outcomes were observed in independent correlation with NYHA classification III and IV. Peripartum intensive care unit admission rate of 10.2% was reported. NYHA Classification II/III/IV, modified World Health Organization (mWHO) classification II-III/III/IV, and cardiac surgery during pregnancy were observed to be correlated with admission to intensive care unit. Based on these observation, they conclude that risk of complications for both women and neonates was higher in correlation with pregnancy with heart disease.

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