Preeclampsia is a valuable opportunity to diagnose chronic kidney disease: A multicentre study
Nephrology Dialysis Transplantation Aug 05, 2021
Cabiddu G, Mannucci C, Fois A, et al. - The prevalence of newly diagnosed chronic kidney disease (CKD) is high in a large multicenter cohort of women without acknowledged CKD who experienced a preeclampsia (PE) (19% vs expected 3% in women in childbearing age). This supports a systematic nephrology work-up after PE.
The KDOQI guidelines were followed to define CKD; urinary alterations or low eGFR confirmed at least 3 months of distance, or morphologic changes.
Division of patients into 4 groups was done: evidence of CKD; no evidence of CKD; unclear diagnosis-ongoing work-up; persistent microalbuminuria.
France (Le Mans, Central France) and Italy (Cagliari, Sardinia) were identical in incidence of CKD diagnosis (Le Mans: 19.1%; Cagliari: 19.2%) and had no significant difference in unclear-ongoing diagnosis (6.2%; 5.8%) and microalbuminuria (10.5%; 5.8%).
There were more frequent occurrences of glomerulonephritis and diabetic nephropathy in Cagliari (higher age and diabetes prevalence) and interstitial diseases in Le Mans.
Patients diagnosed with CKD had one week shorter gestation.
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