Entezari V, et al. - This study sought to evaluate the predictors of traumatic nerve injury and recovery in a large cohort of patients with humeral shaft fractures. After obtaining IRB approval, researchers retrospectively enrolled a total of 376 patients with humeral shaft fracture including 96 patients with documented traumatic nerve palsy and 280 with the intact neurovascular exam on presentation. The primary endpoint included incidence of a traumatic nerve palsy and nerve recovery was considered as the secondary endpoint. The data exhibited that after humeral shaft fracture, the incidence of nerve injury was 25%, reflecting an abundance of high energy and open injuries in this cohort. It was shown that 91% of individuals experienced an improvement in their nerve function with the median time to recovery of 7-9 weeks. The rate of nerve recovery was not changed by the operative treatment of the fracture. The outcomes indicated that individuals with multiple nerve palsies and concurrent vascular insult had worse nerve recovery. In addition, they recommend nerve studies whether no sign of recovery is observed by 9 weeks.