Predictors of revision, prosthetic joint infection and mortality following total hip or total knee arthroplasty in patients with rheumatoid arthritis: A nationwide cohort study using Danish healthcare registers
Annals of Rheumatic Diseases Nov 06, 2017
Cordtz RL, et al. - A nationwide cohort study is carried out to explore predictors of 10-year risk of revision and 1-year risk of prosthetic joint infection (PJI) and death following total hip/total knee arthroplasty (THA/TKA) in (1) patients with rheumatoid arthritis (RA) compared with patients with osteoarthritis (OA); and (2) patients with RA treated with biological disease-modifying antirheumatic drugs (bDMARD) within 3 months preceding surgery compared with non-treated. It was concluded that the patients with RA had a reduced 10-year risk of revision while the risk of death and PJI was increased compared with patients with OA following THA/TKA. bDMARD exposure was not related to the statistically significant increased risk of neither PJI nor death in this study. Glucocorticoid exposure and increased disease activity were related to an increased risk of death.
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