Miyoshi T, Ito H, Shirai K, et al. - A higher cardio‐ankle vascular index (CAVI) (≥9.50) in patients with cardiovascular disease (CVD) risk factors was associated with elevated risks of cardiovascular events, and thus, CAVI affords a clinically useful predictor of cardiovascular events in such patients.

• A prospective cohort study was conducted with 2,932 patients (aged 40‒74 years) with cardiovascular disease risks.

• The primary outcome was the composite of cardiovascular death, nonfatal stroke, or nonfatal myocardial infarction.

• Of these, 82 had an occurrence of primary outcome during a median follow‐up of 4.9 years.

• Primary outcome was predicted by CAVI (hazard ratio, 1.38; 95% CI, 1.16‒1.65; P<0.001).

• CAVI was linked with cardiovascular death and stroke but not with myocardial infarction.