Xia X, Li K, Wu R, et al. - among patients with limited‐stage small cell lung cancer (LD‐SCLC), researchers assessed if neuron‐specific enolase (NSE), neutrophil‐to‐lymphocyte ratio (NLR), and lymph node metastasis can predict distant metastasis by retrospectively examining clinical pathological data of LD‐SCLC patients. Researchers compared 47 cases with distant metastasis and 47 cases without distant metastasis in terms of age, gender, smoking, TNM, NSE, NLR, chemotherapy cycle, radiotherapy, surgery, and new metastasis of lymph nodes during 1 year. Experts found that distant metastasis was predicted by new lymph node metastasis, NLR and NSE, which may profoundly influence treatment decision making. A lower distant metastasis rate was observed in patients who exhibited lower NLR and NSE expression levels and had less new metastasis of lymph nodes.