Rindi LV, Al Moghazi S, Donno DR, et al. - Given an increased risk of developing pulmonary embolism (PE) among patients with SARS-CoV2 infection, researchers sought to summarize the literature on predicting rules for PE in hospitalized COVID-19 patients (HCPs) via performing this systematic review.

• A refined pool of 12 studies was retrieved, for a total of 5 scoring systems (Wells score, Geneva score, CHADS2/CHA2DS2VASc/M-CHA2DS2VASc, CHOD score, Padua Prediction Score), and 4,526 patients.

• Deep vein thrombosis is not responsible for most PE seen in SARS-CoV2 infection.

• There appeared a limited value of prediction rules for PE to correctly identify PE in COVID-19.

• CHOD score, which is designed specifically for COVID-19, appears to have a promising predictive ability.

• Overall there is a necessity for generating new prediction rules, specifically developed and validated for determining the risk of PE in HCP, distinguishing ICU from non-ICU patients, and taking into account anticoagulation prophylaxis, comorbidities and the time from COVID-19 diagnosis.