Morales-Arraez D, et al. - Researchers sought factors that can predict not undergoing RNA testing among patients with positive hepatitis C virus (HCV) serology and the effect of incorporating an automated electronic alert with recommendations in clinical practice. They identified requests for 41,403 HCV antibody tests from 34,073 patients. Positive tests were noted for 870 (2.55%) patients. They identified no RNA testing in 37.6% after a median follow-up of 57.0 months (range 45.6-82.1). Primary care serology requests, no history of drug use, and a lack of social support were the independent predictors for not undergoing RNA testing. Following the implementation of an automated alert notification that recommends RNA testing following a positive HCV test and to refer to specialist care, an increase in the rate of RNA testing from 62.4% to 77.7% was seen, indicating the feasibility of its implementation in clinical practice and its value for increasing the rate of RNA testing.