Árnadóttir A, et al. - Authors evaluated if high-sensitivity cardiac troponin T (hs-cTnT) can be used to detect sub-clinical cardiac disease. Participants were without known heart disease and elevated hs-cTnT measured upon presentation to the emergency department. Structural heart disease or ischemic coronary disease was not seen in the majority of patients with hs-cTnT above the 99^th percentile. Nonetheless, signs of coronary disease were seen in 30% of patients, and preventive medical treatment may be beneficial for them. For evaluation of sub-clinical cardiac disease, a better approach might be measuring hs-cTnT in the absence of acute illness.