Sullivan-Mee M, Hedayat M, Charry N, et al. - Researchers desired to know how well clinicians with variable experience may predict the presence and location of 10-2 visual field (VF) loss using structural and functional data that are routinely obtained for glaucoma assessment. Six clinicians were asked to predict the presence and hemispheric location of 10-2 VF loss using 24-2 VF and spectral-domain optical coherence tomography structural data in a test set of 416 eyes (210 patients) with glaucoma suspect or primary open-angle glaucoma (with most eyes having a mild disease). The presence or absence of 10-2 glaucomatous VF loss was highly predictable in this study using standard functional and structural clinical metrics. Such findings imply that 10-2 VF testing is not required to reliably recognize and confirm central VF involvement in the majority of glaucoma eyes. More research is needed to determine whether the error in identifying second hemisphere involvement in 10-2 VF loss is significant.