Lindroth H, et al. - Researchers analyzed data from an ongoing perioperative prospective cohort study of 100 adults (65 y old or older) undergoing noncardiac surgery in order to investigate the predictive value of the National Surgical Quality Improvement Program risk calculation for serious complications (NSQIP-SC) or risk of death (NSQIP-D), and cognitive tests of executive function (Trail Making Tests A and B [TMTA and TMTB]) for postoperative delirium severity. In addition, they described the utility of advanced statistical techniques in the identification of candidate predictors. They analyzed 97 participants with a mean age of 71.68 ± 4.55, 55% male (31/97 CAM+, 32%), and a mean peak Delirium Rating Scale-R-98 of 21.5 ± 6.40. Using the advanced statistical methods of least absolute shrinkage and selection operator and best subsets regression, they identified NSQIP-SC and a measure of executive function, TMTB as predictors of postoperative delirium severity. Increase in the NSQIP-SC score by 10% led to an increase in the peak Delirium Rating Scale Score by 2.9-point.