Kiviniemi AM, et al. – Researchers compared cardiac mortality in patients with coronary artery disease (CAD) and prediabetes with that of patients with normal glycemic status and type 2 diabetes. The study population included patients with CAD after revascularization (79%), optimal medical therapy, or both. Patients were classified as having type 2 diabetes (n=834), impaired glucose tolerance (IGT; n=314), impaired fasting glucose (IFG; n=103), or normal glycemic status (n=697) upon oral glucose tolerance testing. According to results, IGT patients tended to have 49% lower adjusted risk of cardiac death, 32% lower adjusted risk of all-cause mortality, and 36% lower adjusted risk of a major adverse cardiac event (MACE) vs patients with type 2 diabetes. The adjusted risk for all-cause mortality was 82% lower in patients with IFG vs patients with type 2 diabetes, while the risk of cardiac death and MACE were not significantly different between the two groups. The adjusted risks in patients with IGT and IFG for cardiac death, MACE, and all-cause mortality did not differ significantly from those in patients with normal glycemic status. Overall, the authors found that cardiac mortality or incidence of MACE in prediabetic CAD patients did not differ from those in normal glycemic patients.