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Posttreatment squamous cell carcinoma antigen predicts treatment failure in patients with cervical squamous cell carcinoma treated with concurrent chemoradiotherapy

Gynecologic Oncology Oct 04, 2019

Wang W, Liu X, Hou X, et al. - Researchers analyzed patients treated with concurrent chemoradiotherapy for cervical squamous cell carcinoma (SCC), to determine the link between posttreatment SCC Ag (antigen) and treatment failure. They evaluated the cutoff value of posttreatment SCC Ag in predicting treatment failure by using a receiver operating characteristic curve. The value of posttreatment SCC Ag in predicting disease-free survival was assessed using log-rank tests and Cox proportional hazards models. They analyzed overall 559 patients. A high rate of treatment failure and poor survival was observed in patients with posttreatment SCC Ag ≥ 1.8 ng/mL.
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