Garg R, Mohan BP, Ponnada S, et al. - The rate of postoperative complications in individuals who were exposed to ustekinumab (UST) before surgery may be similar to that seen with anti-tumor necrosis factor (TNF) medication. The risk of postoperative complications is influenced by preoperative UST exposure.

• In total, 5 studies were involved in the analysis.

• The medicine was last taken at least 16 weeks before the abdomino-pelvic surgery.

• The sample consisted of 172 Crohn disease patients (61% female; median age 35 years).

• Any complications and any infectious complications had a pooled rate of 23.5% and 20.2%, respectively.

• There were no differences in intra-abdominal sepsis rates between the UST and anti-TNF groups.

• In the UST group, readmission and reoperation rates were 17.4% and 14.6%, respectively.