Mousa AK, Elshenawy AA, Maklad SM, et al. - According to this prospective study, the best prognostic factors were early accurate diagnosis, low-grade malignancy, and well-planned individualized surgery with adjuvant radiotherapy. Close monitoring for early signs of disease recurrence is critical.

• After adequate ulcer debridement, 19 cases were proven to have Marjolin's ulcer, and the other cases that had been ruled out as malignant underwent reconstruction with split-thickness skin graft with/without flap.

• The anatomic position of the lesions varied, with a predilection for the upper extremity, the scalp, and the lower extremity.

• Although surgical excision is the primary treatment option for tumor ablation, additional factors may influence the treatment plan.

• Eight cases had a neoplastic recurrence in the form of lymph node enlargement and/or locoregional metastasis throughout the follow-up period.

• Six recurrent cases died within a year of the intervention, and two were saved.

• Aside from the case study, this publication examined the literature and gave the team a positive experience in light of the National Comprehensive Cancer Network protocol for non-melanotic cutaneous carcinoma, despite the restricted medical resources.