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Plasma 25-hydroxyvitamin D concentrations are inversely associated with all-cause mortality among a prospective cohort of Chinese adults aged ≥80 years

The Journal of Nutrition Apr 10, 2019

Mao C, et al. – In this prospective cohort study involving 2,185 Chinese older adults (aged ≥ 80 years), researchers examined the link between plasma 25-hydroxyvitamin D (25[OH]D) concentration and all-cause mortality via Cox proportional hazards regression models, with adjustments for potential sociodemographic and lifestyle confounders and biomarkers. They estimated HR and 95% CIs to assess the association. At baseline, the detected median plasma 25(OH)D level was 34.4 nmol/L. Participants were observed over 5,466 person-years of follow-up, during which time 1,100 deaths were reported. Reduced risk of all-cause mortality was observed in relation to a higher plasma 25(OH)D concentration in this population.

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