Henning DJ, Bhatraju PK, Johnson NJ, et al. - In critically ill emergency department patients, researchers ascertained if biomarkers of endothelial activation and inflammation provide added value for prediction of in-hospital mortality within 28 days when combined with physician judgment. For this prospective, observational study, 421 patients were screened and 314 were enrolled. According to findings, predicting in-hospital mortality in critically ill emergency department patients within 28 days can be improved by including biomarkers of endothelial activation and inflammation in combination with doctor emergency department judgment.