Redig L, Feter N, Dumith SC, et al. - This study was conducted with the aim to examine if and how physical activity during early life associates with the risk of depression in later stages of adulthood.

• Researchers used data from a birth cohort (the 1958 National Child Development Survey), including births (N = 17,415) in England, Wales, and Scotland.

• After birth, follow-ups were performed 11 more times between ages 7 and 62 years (2020).

• The risk of incident elevated depressive symptoms remained reduced throughout adulthood among those who were physically active at age 16 years.

• Physical activity practiced at age 16 years had long-term impacts that persisted throughout adulthood up to age 62 years.