Rees-Punia E, et al. - Via the Cancer Prevention Study-II Nutrition Cohort among 109,030 cancer-free participants, the researchers examined associations of moderate-to-vigorous physical activity (MVPA) and sitting with the risk of myeloid neoplasms (MN) or MN subtypes. No statistically significant association for higher MVPA was noted. However, meeting/doubling guidelines was related to a lower risk of myelodysplastic syndromes (MDS). Hence, it was concluded that MVPA was not associated with the risk of myeloid leukemia or AML. Furthermore, sitting time was not associated with the risk of any outcome. Certainly, there could be a nonlinear association between MVPA and risk of MDS and possibly other MN.