Ioroi T, et al. - The ability of palonosetron, aprepitant and dexamethasone in preventing nausea and vomiting induced by 5-day cisplatin-based combination chemotherapy in patients with testicular germ cell tumours (TGCTs) was assessed in this open-label, single-arm, single-centre study. On the basis of the Common Terminology Criteria for Adverse Events v4.0 and a subjective rating scale completed by patients, the incidence and severity of nausea were assessed. Efficacy, as well as good tolerability of the examined combination antiemetic therapy (palonosetron 0.75 mg on day 1, aprepitant 125 mg on day 1 and 80 mg on days 2–7 and dexamethasone 6.6 mg on days 1–7) was shown in patients with TGCTs receiving 5-day cisplatin-based combination chemotherapy.