López-Valverde ME, et al. - In this retrospective cohort study, the researchers intended to explore the perioperative and long-term mortality of patients with diabetes who undergo lower extremity amputation (LEA) in Spain. From January 1, 2005, to December 31, 2015, all subjects who underwent LEAs were included in San Jorge Hospital, Huesca, Spain. Using the national death index, the live status of every patient up to September 2017 and the date of death were retrieved. It was observed in the findings that long-term survival was worse in patients who underwent a major amputation with a 5-year mortality of 65.6%. However, this mortality was worse than what has been reported for some types of common malignancies.