Beydoun HA, et al. - Among a nationally representative sample of US adults, researchers explored the connections between periodontitis, hours of sleep and white blood cell (WBC) markers. A Cross-sectional study utilizing existing demographic, examination, laboratory and questionnaire data on 11,813 candidates from the 2009-2014 National Health and Nutrition Examination Surveys. Data reported that the weighted mean WBC count was 7,130 cells/μl, with the WBC 5-part differential estimated in terms of percentages of lymphocytes (29.50%), monocytes (7.99%), neutrophils (59.03%), eosinophils (2.84%) and basophils (71.88%). In addition, 36.2% of candidates reported < 7 hours of sleep and 49.8% had periodontitis. According to findings, periodontitis can be directly correlated with WBC count and %neutrophils and inversely linked to %lymphocytes, particularly among men and people reporting ≥ 7 hours of sleep, with implications for primary and secondary prevention.