Zhao D, et al. - In this 18-year retrospective cohort study, authors assessed 488 individual dental folders from 17,400 dental hospital attendees to estimate the risk for onset of systemic comorbidities due to poor periodontal status. During the 18-year follow-ups, they found significantly higher numbers of the eight comorbidities/mortality (diabetes, cardiovascular disease, chronic obstructive pulmonary disease, cancer, stroke, cognitive impairment, hypertension, and dyslipidemia) in candidates with worse periodontal status on their first registration vs their counterparts. They noted an independent association of bone level (seen as bone loss/age) with the comorbidity profiles. It implied a greater number of comorbidities in people with more bone resorption vs their counterparts. Worse periodontal conditions according to four parameters employed (community periodontal index, BL, bone loss/age and number of remaining teeth) were seen with those with onsets of more comorbidities.