Xiang X, et al. - In this study, researchers explored personal care aides (PCAs)’ knowledge, beliefs, and attitudes towards late-life depression and their experience caring for older adults with depression via performing an online survey (n = 87) and semi-structured interviews (n = 22). They recruited survey respondents employing convenience sampling and interviewees employing purposive sampling from private duty home care agencies in Michigan. In discordance with the current scientific view, most PCAs undervalued suicide rate among older adults, overestimated self-help ability of the depressed person, underrated difficulty diagnosing depression, and attributed depression to personality flaws. However, PCAs showed practice behaviors that were largely consistent with the principles of evidence-based practice for depression. By PCAs, psychotherapy and informal support were favored, medication is generally regarded as unhelpful, particularly in mild/moderate depression. To mobilize the large number of PCAs to promote the mental health outcomes of hard-to-reach older adults, they identified the essentiality of specialized mental health training, a standard depression care protocol, and higher training standards.