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Patterns of insulin therapy and insulin daily doses in children and adolescents with type 1 diabetes in Germany

Diabetes, Obesity and Metabolism Oct 27, 2021

van den Boom L, Kostev K, et al. - This cross-sectional study was conducted to describe the different insulin therapy patterns and insulin daily doses in children and adolescents (age 1–17 years) with type 1 diabetes.

  • From the LRx database (IQVIA), researchers included 22,512 children and adolescents (mean age: 13.5 years, 47.1% female) who received at least two insulin prescriptions of the same drug.

  • Overall there was a marked age dependency for pump use with a strong rise observed in the youngest age group.

  • With age, there was a reduction in the proportion of patients using insulin pump therapy, from 72.6% (females) and 73.0% (male) in the age group < 6 years to 30.8% (females) and 26.1% (males) in adolescents.

  • The most common short-acting insulin was insulin aspart; there was an increase in the proportion of users from 56% in the age group < 6 years to 69%–70% in the age group 13–17 years.

  • Relative to multiple daily injections (MDI), the daily dose of insulin pump therapy was 10 units lower.

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