Abuabara K, Ye M, Margolis DJ, et al. - A subgroup of patients showed a high probability of atopic eczema continuing into adulthood whereas it decreased for others; additional research is supported for a newly discovered subgroup with increasing probability of activity in adulthood.

• A total of 30,905 participants from 2 population-based birth cohorts were evaluated from birth into midlife to determine whether there are patterns of atopic eczema activity that continue into adulthood.

• Four patterns of activity for atopic eczema were revealed across ages: high probability, decreasing, increasing, and low probability.

• Early life factors failed to distinguish the high from the decreasing subtype.

• The probability of developing asthma and rhinitis was the greatest in those in the high subtype, and there was a higher risk of poor self-reported general (odds ratio [OR], 1.29) and mental (OR 1.45) health in midlife in those in the increasing subtype.