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Patient satisfaction of propofol vs midazolam and fentanyl sedation during colonoscopy in inflammatory bowel disease

Clinical Gastroenterology and Hepatology Oct 26, 2020

Steenholdt C, Jensen JT, Brynskov J, et al. - Due to unpleasantness related colonoscopy, many patients opt out of this procedure despite its essentiality for optimal management of inflammatory bowel disease (IBD). Researchers here examined if patient satisfaction and attitude towards future colonoscopies improves in correlation with nurse Administered Propofol Sedation (NAPS). They conducted a randomized clinical trial including 56 patients (43%) with ulcerative colitis, 48 (37%) with Crohn’s disease, and 26 (20%) with high suspicion of IBD; the participants underwent deep sedation with NAPS (n = 63) or moderate midazolam and fentanyl sedation (n = 67). Per findings, deep propofol sedation was favored by IBD patients over moderate midazolam and fentanyl sedation. Patient adherence to endoscopy-based monitoring programs may improve with availability of NAPS.

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