Zhao CL, Rapkiewicz A, Maghsoodi-Deerwester M, et al. - To assess how COVID-19 infection manifests in the liver, experts examined histopathologic findings in postmortem hepatic tissue, immunohistochemical staining with antibody against COVID spike protein, CD68 and CD61, and electron microscopy. Researchers obtained the clinical data from 17 autopsy cases of COVID-19 patients including age, gender, BMI, liver function test (ALT, AST, ALP, direct bilirubin, and total bilirubin), D-dimer, and anticoagulation treatment. In 12/17 cases of COVID-19 infection, abnormal liver-associated enzymes were observed. Other than three cases that were not tested for D-dimer, D-dimer levels all 14 patients were increased, including the cases that received various doses of anticoagulation treatment. The results of this study demonstrated that the characteristic findings in COVID-19 patients’ liver include numerous amounts of platelet-fibrin microthrombi as well as various degrees of steatosis and histiocytic hyperplasia in the portal tract. They also discussed possible mechanisms.