Yuh EL, Jain S, Sun X, et al. - In mild traumatic brain injury (mTBI) cases, different pathological features on head computed tomography (CT) had different implications for prognosis to 1 year postinjury. Some injury patterns were related to worse outcomes than others. Thus, patients with mTBI and these CT features require TBI-specific education as well as systematic follow-up.

• This longitudinal, observational analysis involved 1,935 patients with mTBI in the TRACK-TBI cohort and 2,594 patients with mTBI in an external validation cohort.

• In both groups, 3 major clusters of CT features were revealed: contusion, subarachnoid hemorrhage, and/or subdural hematoma; intraventricular and/or petechial hemorrhage; and epidural hematoma.

• Co-occurrence of subarachnoid hemorrhage, subdural hematoma, and contusion was often present and these features were related to both incomplete recovery and more severe impairment out to 12 months post-injury.

• Intraventricular and/or petechial hemorrhage co-existed and were related to more severe impairment up to 12 months post-injury.

• Incomplete recovery at some points, but not more severe impairment, was found in relation to epidural hematoma.

• There was a stronger link of some intracranial hemorrhage patterns with outcomes than earlier validated demographic and clinical variables.