Stodulski D, et al. - In this clinicopathological analysis, researchers retrospectively evaluated the treatment outcomes of 40 patients with parotid gland salivary duct carcinoma (SDC). The study sample consisted of patients with an average age of 62 years (ranged from 39 to 81), with male predominance (57.5%). Surgical management was used in all cases, and all but one had supplementary radiotherapy. Disease recurrence was noted in 23 patients (57.5%), local recurrence in 10 (25%) and distant metastases in 15 (37.5%). The estimated 5-year disease-free survival was 42.5% and overall survival was 41%. Clinically aggressive nature of SDC was evident and SDC was shown to have a high risk of local recurrence and distant metastases, however, with a chance of curing of around 40%. The high clinical stage of disease, in the majority of patients, mandated a radical surgical treatment. The patients with preoperative 7th nerve palsy and those in whom SDC developed in pleomorphic adenoma experienced worse prognosis.