Tsimicalis A, et al. - During this prospective, observational study, researchers sought to elucidate the pain and quality of life among children and adolescents with any osteogenesis imperfecta (OI) type over one intravenous bisphosphonate treatment cycle from a child and parental perspective. A total of 33 child/parent dyads took part in this trial. Mild, yet complex pain was experienced by children and adolescents with OI localized across several body areas. Findings disclosed minor fluctuation in the pain intensity and functioning of children with OI undergoing bisphosphonate treatment.