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Oxycodone vs sufentanil in patient-controlled intravenous analgesia after gynecological tumor operation: A randomized double-blind clinical trial

Journal of Pain Research May 08, 2020

Dang SJ, Li RL, Wang J, et al. - Analgesic effect and side effects of oxycodone vs sufentanil were determined in transition analgesia and patient-controlled intravenous analgesia (PCIA) after gynecological tumor operation under general anesthesia via conducting a prospective, randomized, double-blind research. Researchers performed randomization of patients undergoing elective gynecological tumor surgery into four groups: Group S (sufentanil transition analgesia and sufentanil PCIA), Group OS (oxycodone transition analgesia and sufentanil PCIA), Group SO (sufentanil transition analgesia and oxycodone PCIA) and Group O (oxycodone transition analgesia and oxycodone PCIA). Outcomes revealed achievement of adequate pain relief with both oxycodone and sufentanil in transitional analgesia and PCIA treatment after surgery. Less analgesic drug consumption and faster recovery were observed in correlation with receiving oxycodone without background infusion vs sufentanil with background infusion in PCIA after gynecological tumor operation under general anesthesia.

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